These tools were developed to facilitate circular RNA analysis. Welcome to use and cite these tools!


Zhang XO*, Wang HB*, Zhang Y, Lu X, Chen LL#, Yang L#. Complementary sequence-mediated exon circularization. Cell, 2014, 159: 134-147. [Paper] [Github]


Zhang Y*, Zhang XO*, Chen T, Xiang JF, Yin QF, Xing YH, Zhu S, Yang L# and Chen LL#. Circular intronic long noncoding RNAs. Mol Cell, 2013, 51:792-806. [Paper] [Github]


Dong R, Zhang XO, Zhang Y, Ma XK, Chen LL and Yang L. CircRNA-derived pseudogenes. Cell Res, 2016, 15:611-624. [Paper] [Github]


Dong R*, Ma XK*, Chen LL# and Yang L#. Increased complexity of circRNA expression during species evolution. RNA Biol, 2017, 14:1064-1074 [Paper] [Github]


Ma XK*, Wang MR, Liu CX, Dong R, Carmichael GG, Chen LL and Yang L#. A CLEAR pipeline for direct comparison of circular and linear RNA expression. 2019, bioRxiv. doi: 10.1101/668657 [Paper] [Github]



Zhang XO*, Dong R*, Zhang Y*, Zhang JL, Luo Z, Zhang J, Chen LL#, Yang L#. Diverse alternative back-splicing and alternative splicing landscape of circular RNAs. Genome Res, 2016, 26:1277-1287 [Paper]

Dong R*, Ma XK*, Li GW, Yang L#. CIRCpedia v2: An Updated Database for Comprehensive CircRNA Annotation and Expression Comparison. Genomics Proteomics Bioinformatics, 2018, doi:10.1016/j.gpb.2018.08.001 [Paper]